Quintero has been catching three starters -- Danny Duffy, Jonathan Sanchez and Luke Hochevar -- and Pena has been working with the other two, Bruce Chen and Luis Mendoza.
"The reason I like that is, when you've got an everyday catcher, you've got a chance to build some rapport with your pitcher from time to time to time," Yost said.
"If you've got two guys that are going to catch I think it's more important to put them with the [same] guys so they develop that relationship. They know what worked last time, they know what didn't work and they start to think with them and it just makes it easier."
Quintero, acquired from the Astros late in Spring Training, is getting used to his new surroundings and to his part-time schedule.
"I've done it before when I played two, three or four times a week. Sometimes I played every day, so I'm available to do everything," Quintero said. "I feel comfortable right now."
Pena, a switch hitter, has a good reputation with a bat so his .304 (7-for-23) average isn't unexpected. But Quintero, known more for his defense, went into Sunday's game against the Blue Jays with a .320 (8-for-25) mark that included four doubles and three RBIs.
"He's been pretty impressive with the bat so far, he's been a bit of a surprise," Yost said.