Although Quintero normally would have caught Danny Duffy if he had pitched on Friday night, Pena got the assignment with spot starter Everett Teaford.
"It was a good day yesterday to give Quintero a break," manager Ned Yost said. "He's been bothered with a little hip soreness and some back tightness. If it was Duffy throwing yesterday, 'Q' would have started. Because it was Teaford, it was a good chance to give him a bit of a break."
With Saturday's game rained out, that means Pena will be paired with veteran Bruce Chen in Sunday's series finale. Quintero was expected to return on Monday night at Detroit, catching Jonathan Sanchez.
The normal pairings are Pena with Chen and Luis Mendoza; Quintero with Duffy, Sanchez and Luke Hochevar.