Manager Ned Yost said that during the regular season, Moustakas probably would be in the lineup.
"But we're going to give him a day to get treatment on it," Yost said. "Nothing needs to be nagging this time of year."
Likewise, Escobar is also expected to miss just one day.
Elliot Johnson replaced Escobar at shortstop, and Anthony Seratelli took over for Moustakas at third.
Dick Kaegel is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.