The total before Wednesday included 186 by James Shields, 159 by Ervin Santana, 112 by Wade Davis, 107 by Jeremy Guthrie and 99 by Greg Holland.
Holland's 99 came in just 65 innings, putting him four Ks shy of Jim York's club record for a reliever (103 in 1971). York got his total in 93 1/3 innings.
Dick Kaegel is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.